Publikations

Publications in Journals (60)

2020
[60], , . PySCNet: A tool for reconstructing and analyzing gene regulatory network from single-cell RNA-Seq data. Cold Spring Harbor Laboratory; 2020. doi: 10.1101/2020.12.18.423482 [BibTeX]
[59], , , , , , , , , , , , , , , , . NOX5-induced uncoupling of endothelial NO synthase is a causal mechanism and theragnostic target of an age-related hypertension endotype. PLOS Biology. Public Library of Science (PLoS); 2020;18(11):e3000885. doi: 10.1371/journal.pbio.3000885 [BibTeX]
[58], , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , . The Polygenic and Monogenic Basis of Blood Traits and Diseases. Cell. Elsevier BV; 2020;182(5):1214–1231.e11. doi: 10.1016/j.cell.2020.08.008 [BibTeX]
[57], , , , , . miRNA Alterations Elicit Pathways Involved in Memory Decline and Synaptic Function in the Hippocampus of Aged Tg4-42 Mice. Frontiers in Neuroscience. Frontiers Media SA; 2020;14. doi: 10.3389/fnins.2020.580524 [BibTeX]
[56], , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , . Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746, 667 Individuals from 5 Global Populations. Cell. Elsevier BV; 2020;182(5):1198–1213.e14. doi: 10.1016/j.cell.2020.06.045 [BibTeX]
[55], , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , . Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. Diabetes. American Diabetes Association; 2020;69(12):2806–2818. doi: 10.2337/db20-0070 [BibTeX]
[54], , , , , , , . DIGGER: exploring the functional role of alternative splicing in protein interactions. Nucleic Acids Research. Oxford University Press (OUP); 2020;49(D1):D309–D318. doi: 10.1093/nar/gkaa768 [BibTeX]
[53], , , , , , , , , , , , , . The Gut Microbiome in Patients With Chronic Pancreatitis Is Characterized by Significant Dysbiosis and Overgrowth by Opportunistic Pathogens. Clinical and Translational Gastroenterology. Ovid Technologies (Wolters Kluwer Health); 2020;11(9):e00232. doi: 10.14309/ctg.0000000000000232 [BibTeX]
[52], , , , , , , , , , . Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing. Nature Communications. Springer Science and Business Media LLC; 2020;11(1). doi: 10.1038/s41467-020-17189-2 [BibTeX]
[51], , , , , , , , , , , , , , , , . Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing. Nature Communications. Springer Science and Business Media LLC; 2020;11(1). doi: 10.1038/s41467-020-17189-2 [BibTeX]
[50], , , , , , , , , , , . sPLINK: A Federated, Privacy-Preserving Tool as a Robust Alternative to Meta-Analysis in Genome-Wide Association Studies. Cold Spring Harbor Laboratory; 2020. doi: 10.1101/2020.06.05.136382 [BibTeX]
[49], , , , . Importance of considering the growth response after partial harvesting and economic risk of discounted net revenues when optimizing uneven-aged forest management. Canadian Journal of Forest Research. Canadian Science Publishing; 2020;50(5):487–499. doi: 10.1139/cjfr-2018-0546 [BibTeX]
[48], , , , , . EpiGEN: an epistasis simulation pipeline. Bioinformatics. Oxford University Press (OUP); 2020;36(19):4957–4959. doi: 10.1093/bioinformatics/btaa245 [BibTeX]
[47], , , , , , , . Comparative single-cell trajectory network enrichment identifies pseudo-temporal systems biology patterns in hematopoiesis and CD8 T-cell development. Cold Spring Harbor Laboratory; 2020. doi: 10.1101/2020.04.02.021295 [BibTeX]
[46], , , , , , , , , , , , , , , . Molecular markers in the CSF proteome differentiate neuroinflammatory diseases. Research Square; 2020. doi: 10.21203/rs.3.rs-19710/v1 [BibTeX]
[45], , , , , , , , , , , . Association of proteome and metabolome signatures with severity in patients with community-acquired pneumonia. Journal of Proteomics. Elsevier BV; 2020;214:103627. doi: 10.1016/j.jprot.2019.103627 [BibTeX]
[44], , , , , , , , . BiCoN: Network-constrained biclustering of patients and omics data. Cold Spring Harbor Laboratory; 2020. doi: 10.1101/2020.01.31.926345 [BibTeX]
[43], , , , , , , , , , , , , , , , , , , , , , , , , , , . DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning. PLOS Computational Biology. Public Library of Science (PLoS); 2020;16(2):e1007616. doi: 10.1371/journal.pcbi.1007616 [BibTeX]
[42], , , , , , , , , , , , , , , , , , , , , , , , , . Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans. Nature Genetics. Springer Science and Business Media LLC; 2020;52(2):167–176. doi: 10.1038/s41588-019-0567-8 [BibTeX]
2019
[41], , , , , , , , . Molecular signature of different lesion types in the brain white matter of patients with progressive multiple sclerosis. Acta Neuropathologica Communications. Springer Science and Business Media LLC; 2019;7(1). doi: 10.1186/s40478-019-0855-7 [BibTeX]
[40], , , , , , , , , , , , , , , , , , , , , , , , . Obese Individuals with and without Type 2 Diabetes Show Different Gut Microbial Functional Capacity and Composition. Cell Host & Microbe. Elsevier BV; 2019;26(2):252–264.e10. doi: 10.1016/j.chom.2019.07.004 [BibTeX]
[39], , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , . Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease. PLOS ONE. Public Library of Science (PLoS); 2019;14(5):e0216222. doi: 10.1371/journal.pone.0216222 [BibTeX]
[38], , , , , , , , , . MS Atlas - A molecular map of brain lesion stages in progressive multiple sclerosis. Cold Spring Harbor Laboratory; 2019. doi: 10.1101/584920 [BibTeX]
[37], , , , , , , , , , , , , , , , . Impaired Exocrine Pancreatic Function Associates With Changes in Intestinal Microbiota Composition and Diversity. Gastroenterology. Elsevier BV; 2019;156(4):1010–1015. doi: 10.1053/j.gastro.2018.10.047 [BibTeX]
[36], , , , , , , , , , . Associations of autozygosity with a broad range of human phenotypes. Nature communications. Nature Publishing Group; 2019;10(1):1–17. [BibTeX]
2018
[35], , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , . Genome Analyses of $\greater$200, 000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders. The American Journal of Human Genetics. Elsevier BV; 2018;103(5):691–706. doi: 10.1016/j.ajhg.2018.09.009 [BibTeX]
[34], , . Empowering thyroid hormone research in human subjects using OMICs technologies. Journal of Endocrinology. Bioscientifica; 2018;238(1):R13–R29. doi: 10.1530/joe-18-0117 [BibTeX]
[33], , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , . DNA methylation as a mediator of HLA-DRB1\ast15:01 and a protective variant in multiple sclerosis. Nature Communications. Springer Science and Business Media LLC; 2018;9(1). doi: 10.1038/s41467-018-04732-5 [BibTeX]
[32], , , , , , , , , , , , , , , , , , , , , , , , , . Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative. Microbiome. Springer Science and Business Media LLC; 2018;6(1). doi: 10.1186/s40168-018-0479-3 [BibTeX]
[31], , , , , , , , , , , . Functional abdominal pain and discomfort (IBS) is not associated with faecal microbiota composition in the general population. Gut. BMJ; 2018;68(6):1131.1–1133. doi: 10.1136/gutjnl-2018-316502 [BibTeX]
[30], , , , , , , , , , . MicroRNA analysis of gastroenteropancreatic neuroendocrine tumors and metastases. Oncotarget. Impact Journals, LLC; 2018;9(47):28379–28390. doi: 10.18632/oncotarget.25357 [BibTeX]
[29], , , , , , , , , , , , , , , , , , , , , , . A GWAS meta-analysis from 5 population-based cohorts implicates ion channel genes in the pathogenesis of irritable bowel syndrome. Neurogastroenterology & Motility. Wiley; 2018;30(9):e13358. doi: 10.1111/nmo.13358 [BibTeX]
2017
[28], , , , , , , , , , , , , , , , , , , . Evidence for Stress-like Alterations in the HPA-Axis in Women Taking Oral Contraceptives. Scientific Reports. Springer Science and Business Media LLC; 2017;7(1). doi: 10.1038/s41598-017-13927-7 [BibTeX]
[27], , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , . Transcriptome-Wide Analysis Identifies Novel Associations With Blood Pressure. Hypertension. Ovid Technologies (Wolters Kluwer Health); 2017;70(4):743–750. doi: 10.1161/hypertensionaha.117.09458 [BibTeX]
[26], , , , , , , , , , , , , , . Plasma proteome and metabolome characterization of an experimental human thyrotoxicosis model. BMC Medicine. Springer Science and Business Media LLC; 2017;15(1). doi: 10.1186/s12916-016-0770-8 [BibTeX]
2016
[25], , , , , , , , , , , , , , , , . Profiling and validation of circulating microRNAs for cardiovascular events in patients presenting with ST-segment elevation myocardial infarction. European Heart Journal. Oxford University Press (OUP); 2016:ehw563. doi: 10.1093/eurheartj/ehw563 [BibTeX]
[24], , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , . Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Nature Genetics. Springer Science and Business Media LLC; 2016;49(1):125–130. doi: 10.1038/ng.3738 [BibTeX]
[23], , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , . Gene-gene Interaction Analyses for Atrial Fibrillation. Scientific Reports. Springer Science and Business Media LLC; 2016;6(1). doi: 10.1038/srep35371 [BibTeX]
[22], , , , , , , , , , , , , , , , , , , , , , , . Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior. Human Molecular Genetics. Oxford University Press (OUP); 2016:ddw334. doi: 10.1093/hmg/ddw334 [BibTeX]
[21], , , , , . Notions of similarity for systems biology models. Briefings in Bioinformatics. Oxford University Press (OUP); 2016:bbw090. doi: 10.1093/bib/bbw090 [BibTeX]
[20], , , , , , , , , , , . Exome Variant Analysis of Chronic Periodontitis in 2 Large Cohort Studies. Journal of Dental Research. SAGE Publications; 2016;96(1):73–80. doi: 10.1177/0022034516665076 [BibTeX]
[19], , , , , , , , . Transcriptome Alterations In X-Irradiated Human Gingiva Fibroblasts. Health Physics. Ovid Technologies (Wolters Kluwer Health); 2016;111(2):75–84. doi: 10.1097/hp.0000000000000419 [BibTeX]
[18], , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , . Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases. The American Journal of Human Genetics. Elsevier BV; 2016;99(1):22–39. doi: 10.1016/j.ajhg.2016.05.003 [BibTeX]
[17], , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , . Platelet-Related Variants Identified by Exomechip Meta-analysis in 157, 293 Individuals. The American Journal of Human Genetics. Elsevier BV; 2016;99(1):40–55. doi: 10.1016/j.ajhg.2016.05.005 [BibTeX]
[16], , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , . Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits. The American Journal of Human Genetics. Elsevier BV; 2016;99(1):8–21. doi: 10.1016/j.ajhg.2016.05.007 [BibTeX]
[15], , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , . Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation. Science Advances. American Association for the Advancement of Science (AAAS); 2016;2(6):e1501678. doi: 10.1126/sciadv.1501678 [BibTeX]
[14], , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , . Inferring causal molecular networks: empirical assessment through a community-based effort. Nature Methods. Springer Science and Business Media LLC; 2016;13(4):310–318. doi: 10.1038/nmeth.3773 [BibTeX]
[13], , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , . Gene transcripts associated with muscle strength: a CHARGE meta-analysis of 7, 781 persons. Physiological Genomics. American Physiological Society; 2016;48(1):1–11. doi: 10.1152/physiolgenomics.00054.2015 [BibTeX]
2015
[12], , , , , , , . Gene Expression Profiling in the APP/PS1KI Mouse Model of Familial Alzheimer’s Disease. Journal of Alzheimer’s Disease. IOS Press; 2015;50(2):397–409. doi: 10.3233/JAD-150745 [BibTeX]
[11], , , , , , , , , , . Associations of circulating plasma microRNAs with age, body mass index and sex in a population-based study. BMC Medical Genomics. Springer Science and Business Media LLC; 2015;8(1). doi: 10.1186/s12920-015-0136-7 [BibTeX]
[10], , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , . Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF. Blood. American Society of Hematology; 2015;126(11):e19–e29. doi: 10.1182/blood-2015-02-624551 [BibTeX]
[9], , , , , , , , , , , , , , , , , , , . Genome-Wide Association Study with Targeted and Non-targeted NMR Metabolomics Identifies 15 Novel Loci of Urinary Human Metabolic Individuality. PLOS Genetics. Public Library of Science (PLoS); 2015;11(9):e1005487. doi: 10.1371/journal.pgen.1005487 [BibTeX]
[8], , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , . Directional dominance on stature and cognition in diverse human populations. Nature. Springer Science and Business Media LLC; 2015;523(7561):459–462. doi: 10.1038/nature14618 [BibTeX]
[7], , , , , , , , , , , , , , , , , , , , , , , , , , , , , . Multi-omic signature of body weight change: results from a population-based cohort study. BMC Medicine. Springer Science and Business Media LLC; 2015;13(1). doi: 10.1186/s12916-015-0282-y [BibTeX]
2014
[6], , , , , , , , , , , . Deciphering the Molecular Profile of Plaques, Memory Decline and Neuron Loss in Two Mouse Models for Alzheimerâ\mbox\texteuro\texttrademarks Disease by Deep Sequencing. Frontiers in Aging Neuroscience. Frontiers Media SA; 2014;6. doi: 10.3389/fnagi.2014.00075 [BibTeX]
[5], , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , . Cohort profile: Greifswald approach to individualized medicine (GANI_MED). Journal of Translational Medicine. Springer Science and Business Media LLC; 2014;12(1):144. doi: 10.1186/1479-5876-12-144 [BibTeX]
2013
[4], , , , , , , , , . Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics. PROTEOMICS. Wiley; 2013;13(21):3131–3144. doi: 10.1002/pmic.201300154 [BibTeX]
[3], , . NetworkPrioritizer: a versatile tool for network-based prioritization of candidate disease genes or other molecules. Bioinformatics. Oxford University Press (OUP); 2013;29(11):1471–1473. doi: 10.1093/bioinformatics/btt164 [BibTeX]
2012
[2], , . Recent approaches to the prioritization of candidate disease genes. Wiley Interdisciplinary Reviews: Systems Biology and Medicine. Wiley; 2012;4(5):429–442. doi: 10.1002/wsbm.1177 [BibTeX]
2011
[1], , . Measuring and analyzing tissue specificity of human genes and protein complexes. EURASIP Journal on Bioinformatics and Systems Biology. Springer Science and Business Media LLC; 2011;2011(1). doi: 10.1186/1687-4153-2011-5 [BibTeX]

Publications in Proceedings and as Book Sections (1)

2021
[1], , , , , . Multi-Omics Analysis in a Network Context. Chapter in Systems Medicine. Elsevier; 2021. doi: 10.1016/b978-0-12-801238-3.11647-2 [BibTeX]

Other Publications (1)

2020
[1], , , , , , , , , , , , , , , , , , , , , , , , . Privacy-preserving Artificial Intelligence Techniques in Biomedicine. 2020. [BibTeX]